In the lipid-rich environment of the CNS, ferroptosis could therefore play a significant role in secondary damage, the neuron-astrocyte interaction is also critical for maintaining brain lipid metabolism, indicating that neurons may be more sensitive to drastic changes in lipid peroxidation, moreover, lipid peroxidation contributes to secondary damage after SCI and highlights the possible use of lipid metabolism regulator to treat SCI [46,47,48]
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Improved Recovery and Healing: Ibutamoren MK-677's ability to stimulate GH and IGF-1 can expedite tissue repair and recovery from injuries
Gut flora-dependent metabolite Trimethylamine-N-oxide accelerates endothelial cell senescence and vascular aging through oxidative stress
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Injury recovery Investigated in rodent research on recovery from musculoskeletal injuries
