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This increase in the feeling of satiety, provided by leptin, leads to leptin blocking ghrelin and reducing the indirect feeling of pleasure during food intake

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Pancreas-related risks: a) Acute Pancreatitis: There have been reports of acute pancreatitis, including fatal and non-fatal hemorrhagic or necrotizing pancreatitis, in patients treated with GLP-1 receptor agonists

33.44 mg gallic acid/g for 2-month-old leaves and 21.42 mg gallic acid/g for 6-month-old leaves, by extraction with 70% acetone [51]

GLP-1s have shown significant potential for weight loss, often resulting in a moderate to substantial reduction in body weight (~15-20%)

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