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If an abnormally high cumulative doses are administered, or the patient has low plasma pseudocholinesterase activity, then Phase I block can progress into Phase II block due to the inclusion of additional mechanisms that come into play when high synaptic levels of succinylcholine are achieved

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Stress Management: Chronic stress keeps the body in a "fight or flight" state, which constricts blood vessels

Shadforth, I

Immunohistochemistry for cytotoxic molecules (such as granulysin, perforin, and granzyme B), CD4 and Treg can help differentiate SJS/TEN from EMM [69]