Dual GLP1 and GIP agonists Tirzepatide is a once weekly, subcutaneous, unimolecular dual RA (GLP-1 and GIP) which has comparable GIP receptor binding affinity to native GIP and 5 times lower GLP-1 receptor affinity than that of native GLP-1
However, its worth noting that the cost of oral medications goes up by $100/month if you need a higher dose
Preservation of Lean Muscle Mass By stabilizing blood glucose and optimizing insulin sensitivity, GLP-1 promotes the use of glucose and fat for energy efficiently, helping preserve muscle tissue while prioritizing fat loss
It contains three patented, plant-based ingredients, each with its own small clinical study behind it: Eriomin (lemon bioflavonoids): shown to slightly increase natural GLP-1 levels in people with elevated blood sugar [1] Supresa (saffron extract): linked to reduced snacking in mildly overweight women, although some studies found no significant effects on food cravings [2][3] Morosil (red orange extract): found to support mild fat loss over 12 weeks [4] All three ingredients are studied independently , not as a combined formula
[ref] Carnitine: The study on mice showing that carnitine transport is essential for GLP-1 RA effectiveness indicates that low carnitine levels may impair weight loss.[ref] More studies are needed, but it may be that adding supplemental carnitine could help, especially if you have genetic variants related to lower carnitine levels
Can I take GLP-1 injections at night