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Theyve demonstrated cellular anti-inflammatory effects, such as TNF- and IL-6 downregulation in preclinical models and modulation of COX-2 expression

Currently, there is no practical way to measure individual NNMT activity to predict response

10.3389/fmicb.2023.1155622 39

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A six-month randomized controlled trial showed that daily consumption of glutathione supplements increased GSH levels by 30-35% in erythrocytes, plasma, and lymphocytes