Not all women experience dramatic symptoms during the change
While exact mechanisms remain somewhat unclear, one theory is that ultraviolet light increases plasmin activity in keratinocytes, which leads to an increase in melanocytic-stimulating mediators, such as arachidonic acid and -melanocyte stimulating hormone
Pre-treatment strategies include aggressive hydration starting 48 hours before injection, electrolyte supplementation, and slower dose titration schedules
Li GF, Zhao M, Zhao T, Cheng X, Fan M, Zhu LL (2019) Effects of metformin on depressive behavior in chronic stress rats
the other switches it off
If you have diabetic retinopathy, particularly with semaglutide, additional monitoring may be required